As an abundant natural resource in Asia, bamboo is receiving increased attention as an engineering material due to its renewability and excellent strength. The parallel-to-grain compression and shearing properties of moso bamboo culm were examined. The growth characteristics (bamboo age, nodes, and location along the culm), as well as treatments for practical applications (hole punching and hoop reinforcing by hose clamp) were investigated for their influence. Mechanical tests were conducted in accordance with the ISO22157-1: 2004 (2004), ISO/TR 22157-2:2004(E) (2004), and CNS GB/T 15780-1995 (1996) standards. Acceptable loading rates for the parallel-to-grain compression and shearing tests were 0.1 and 0.05 mm/s, respectively. The compressive and shearing strengths increased from the bottom to the top of the bamboo. Bamboo age and nodes exerted little influence on parallel-to-grain compressive and shearing strength. In addition, hole punches diminished the mechanical strength of the bamboo culm, while hose clamps enhanced it slightly.